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Jan 24, 2023
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Jan 31, 2023
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Abstract




Abstrak


Latar Belakang: Perdarahan Intraserebral (PIS) adalah kumpulan darah dalam parenkim otak atau sistem ventrikel dan bukan karena trauma. Ruptur pembuluh darah kecil dan microaneurysm pada perforasi pembuluh darah merupakan penyebab PIS. Volume perdarahan dan jumlah leukosit merupakan determinan penting untuk functional outcome. Pasien sembuh seringkali memiliki defisit neurologis persisten yang mengganggu aktivitas dan fungsi kesehariannya. Prediktor klinis untuk defisit neurologis dinilai dengan National Institutes of Health Stroke Scale (NIHSS). Tujuan: Penelitian bertujuan mengetahui hubungan antara volume perdarahan dan jumlah leukosit dengan functional outcome PIS di RSPAL dr. Ramelan Surabaya.


Metode: Penelitian berupa analitik observasional dengan desain cross-sectional. Menggunakan metode retrospektif dengan data kuantitatif berupa data sekunder rekam medis pasien rawat inap. Penelitian dilakukan di RSPAL dr. Ramelan Surabaya pada Juni 2021 sampai Juni 2022. Data berasal dari CT scan kepala untuk mengetahui volume pendarahan, hasil laboratorium pemeriksaan darah lengkap untuk mengetahui jumlah leukosit, dan tabel NIHSS untuk mengetahui functional outcome pasien.


Hasil: Penelitian dilakukan pada 50 pasien PIS yang memenuhi kriteria inklusi dan eksklusi. Hasil uji korelasi antara volume perdarahan dan functional outcome pasien menunjukkan ada hubungan yang signifikan dengan nilai signifikansi (p) = 0,02 < α (0,05). Hasil uji korelasi antara jumlah leukosit dan functional outcome pasien menunjukkan tidak ada hubungan yang signifikan dengan nilai signifikansi (p) = 0,798 > α (0,05).


Kesimpulan: Dapat disimpulkan bahwa ada hubungan signifikan antara volume perdarahan dengan functional outcome pasien PIS di RSPAL dr. Ramelan Surabaya. Tidak ada hubungan signifikan antara jumlah leukosit dengan functional outcome pasien PIS di RSPAL dr. Ramelan Surabaya.


Kata kunci: volume perdarahan, jumlah leukosit, Perdarahan Intraserebral (PIS), functional outcome, nilai NIHSS.




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How to Cite
Zeeva, E. J. (2023). HUBUNGAN ANTARA VOLUME PERDARAHAN DAN JUMLAH LEUKOSIT DENGAN FUNCTIONAL OUTCOME PASIEN PERDARAHAN INTRASEREBRAL (PIS) DI RSPAL DR. RAMELAN SURABAYA. Surabaya Biomedical Journal, 2(2), 115-130. https://doi.org/10.30649/sbj.v2i2.61

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