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Abstract
Study aims: Febrile seizures are the most common neurological disorder in children. The incidence of febrile seizures is related to the incidence of epilepsy at 2-4% in the future and the probability of recurrence is about 30% and 50% after the first and second febrile seizures, respectively. Several recent studies have suggested that febrile seizures are more common in children with anemia. Anemia patients who experience febrile seizures can cause more severe clinical manifestations. Where 40.5% of the incidence of anemia in Indonesia occurs in children under the age of 5 years. Therefore, this study is conducted to determine the differences of the clinical manifestations of febrile seizures with and without anemia in children at RSPAL Dr. Ramelan Surabaya on 2019-2022.
Methods: This study was an observational analytic study with a cross-sectional study approach and qualitative methods from secondary medical record data of infants and children aged 6 months-5 years at RSPAL Dr. Ramelan Surabaya for the period May 2019-May 2022. The number of samples in this study was 82 samples.
Results: The characteristics of the sample which experiences the most febrile seizures occurres between the ages of 6-18 months, the gender of male with a temperature >38°C and manifestations in the form of simple febrile seizures. In addition, the results of the fisher exact test with a significance level of 5% shows p = 0.96 which means there is no difference in the clinical manifestations of febrile seizures in anemic and non-anemic children.
Conclusion: The conclusion of this study is that based on the classification of febrile seizures, the most common clinical manifestations that occur in children with anemia and without anemia are simple febrile seizures. So that there is no difference in the clinical manifestations of febrile seizures in anemic children and without anemia.
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References
Family B, Residency M. Febrile Seizures: Risks, Evaluation, and Prognosis. 2012;
[2] Leung AKC, Hon KL, Leung TNH.
Febrile seizures: An overview. Drugs
Context. 2018;7:1–12.
[3] In D, Manifestation C, Febrile O, In S, With C, Fazriansyach H, et al. Perbedaan Manifestasi Klinis Kejang Demam pada Anak Anemia dan Tanpa Anemia di RSUD Al Ihsan Bandung Tahun 2017. 2017;283–9.
[4] Ghasemi F, Valizadeh F, Taee N. Iron-deficiency anemia in children with febrile seizure: A case-control study. Iran J Child Neurol. 2014;8(2):38–44.
[5] Kliegman robert M, W. J, Blum NJ, Shah SS, Wilson KM, Behrman RE. Nelson textbook of pediatrics. BMJ Case Rep. 2021;14(9).
[6] Zbys Fedorowicz, William Aird. Anemia in Adults - Approach to the Patient. 2019;12–8. Available from: https://www-dynamed-com.myaccess.library.utoronto.ca/approach-to/anemia-in-adults-approach-to-the-patient.
[7] Laino D, Mencaroni E, Esposito S. Management of pediatric febrile seizures. Int J Environ Res Public Health. 2018;15(10).
[8] Swaiman KF, Ashwal S, Ferreiro DM, Schor NF, Finkel RS, Gropman AL, et al. Swaiman’s Pediatric Neurology. 2018; 2018.
[9] Pina-garza JE, James KC. Pediatric Neurology Fenichel’s Clinical 8th edition. 2019. 373 p.
[10] Pusponegoro H, Widodo DP, Ismael S (Ikatan DAI. Konsensus Penatalaksanaan Kejang Demam. Ikat Dr Anak Indones [Internet]. 2019;1–23. Available from: http://spesialis1.ika.fk.unair.ac.id/wp-content/uploads/2017/03/Konsensus-Penatalaksanaan-Kejang-Demam.pdf
[11] Zitelli BJ, C S, Nowalk andrew j. Atlas of Pediatric Physical Diagnosis. Vol. 64, Postgraduate Medical Journal. 2017. 89–90 p.
[12] Edition S. Lanzkowsky’s Manual of Pediatric Hematology and Oncology. Lanzkowsky’s Manual of Pediatric Hematology and Oncology. 2022.
[13] Hastings CA, Torkildson JC, Agrawal AK. Handbook of Pediatric Hematology and Oncology: Children’s Hospital & Research Center Oakland: Second Edition. Handbook of Pediatric Hematology and Oncology: Children’s Hospital & Research Center Oakland: Second Edition. 2012.
[14] Lokeshwar M, Shah N, Agrwal B, Manglani M, Sachdeva A, Pillai A, et al. Pediatric Hematolocy & Hemato-Oncology. Vol. 59, the health sciences publisher. 2016.
[15] Sharawat IK, Singh J, Dawman L, Singh A. Evaluation of risk factors associated with first episode febrile seizure. J Clin Diagnostic Res. 2016;10(5):SC10–3.
[16] Helmi M. Perbedaan Manifestasi Klinis Kejang Demam Pada Anak Anemia Dengan Anak Tanpa Anemia. J Kedokteran Diponegoro. 2014;3(1):138487.
[17] Rasyid Z, Astuti DK, Purba CVG. Determinan Kejadian Kejang Demam pada Balita di Rumah Sakit Ibu dan Anak Budhi Mulia Pekanbaru. J Epidemiol Kesehat Indones. 2019;3(1):1–6.
[18] Dasmayanti Y, Anidar A, Imran I, Bakhtiar B, Rinanda T. Hubungan Kadar Hemoglobin dengan Kejang Demam Pada Anak Usia Balita. Sari Pediatr. 2016;16(5):351.
[19] Aswin A, Muhyi A, Hasanah N. Hubungan Kadar Hemoglobin dengan Kejang Demam pada Anak yang Disebabkan Infeksi Saluran Pernapasan Akut: Studi Kasus Kontrol. Sari Pediatr. 2019;20(5):270.
[20] Anidar A, Haris S, Dimiati H. Gambaran Anemia Defisiensi Besi Pada Kejang Demam Di Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh. J Med Sci. 2020;1(2):86–91.